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Mount Massive Asylum for the Criminally Insane is the setting of Outlast and Outlast: Whistleblower. It is located in the remote mountains of Lake CountyColoradoUSA
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The Mount Massive Asylum as it appears in the first trailer.

1945 - The O.S.S. initiates Operation Paperclip, recruiting scientists from Nazi Germany to conduct research for the USA.

1967 - Mount Massive Asylum for the Criminally Insane is established. Three scientists are murdered by an unknown patient. Authorities order the asylum to cease all activities.

1971 - Mount Massive Asylum is finally closed.

1972 - CIA Director Richard Helms orders all MKUltra files to be destroyed. A small number of documentssurvive, scattered throughout the asylum.

2009 - The clinic was re-opened by the Murkoff Corporation, which for the next several years conducts illegal experiments on patients with the sole purpose being profit.